Efflux Pumps, OprD Porin, AmpC β-Lactamase, and Multiresistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients

Expression of ampC, oprD, mexA, mexC, mexE, and mexX was studied in 25 Pseudomonas aeruginosa isolates from cystic fibrosis patients, including 14 isolates of the Liverpool epidemic strain. Overexpressed mexA or ampC and reduced oprD were associated with β-lactam resistance. A specific combination o...

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Bibliographic Details
Main Authors: Tomás, Maria, Doumith, Michel, Warner, Marina, Turton, Jane F., Beceiro, Alejandro, Bou, German, Livermore, David M., Woodford, Neil
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863613/
https://ncbi.nlm.nih.gov/pubmed/20194693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00816-09
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