AmpC and OprD Are Not Involved in the Mechanism of Imipenem Hypersusceptibility among Pseudomonas aeruginosa Isolates Overexpressing the mexCD-oprJ Efflux Pump

Pseudomonas aeruginosa strains that overexpress mexCD-oprJ become hypersusceptible to imipenem. Disruption of AmpC induction has been suggested to cause this phenotype. However, data from this study demonstrate that hypersusceptibility to imipenem can develop without changes in ampC expression or Am...

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Bibliografiska uppgifter
Huvudupphovsmän: Wolter, Daniel J., Hanson, Nancy D., Lister, Philip D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280130/
https://ncbi.nlm.nih.gov/pubmed/16251325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4763-4766.2005
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