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Cell-Specific Determinants of Peroxisome Proliferator-Activated Receptor γ Function in Adipocytes and Macrophages

The nuclear receptor peroxisome proliferator activator receptor γ (PPARγ) is the target of antidiabetic thiazolidinedione drugs, which improve insulin resistance but have side effects that limit widespread use. PPARγ is required for adipocyte differentiation, but it is also expressed in other cell t...

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Autori principali: Lefterova, Martina I., Steger, David J., Zhuo, David, Qatanani, Mohammed, Mullican, Shannon E., Tuteja, Geetu, Manduchi, Elisabetta, Grant, Gregory R., Lazar, Mitchell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863586/
https://ncbi.nlm.nih.gov/pubmed/20176806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01651-09
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