Re-expression of GATA2 Cooperates with Peroxisome Proliferator-activated Receptor-γ Depletion to Revert the Adipocyte Phenotype

Nuclear peroxisome proliferator-activated receptor-γ (PPARγ) is required for adipocyte differentiation, but its role in mature adipocytes is less clear. Here, we report that knockdown of PPARγ expression in 3T3-L1 adipocytes returned the expression of most adipocyte genes to preadipocyte levels. Con...

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Detalhes bibliográficos
Main Authors: Schupp, Michael, Cristancho, Ana G., Lefterova, Martina I., Hanniman, Elyisha A., Briggs, Erika R., Steger, David J., Qatanani, Mohammed, Curtin, Joshua C., Schug, Jonathan, Ochsner, Scott A., McKenna, Neil J., Lazar, Mitchell A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666598/
https://ncbi.nlm.nih.gov/pubmed/19136559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809498200
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