Re-expression of GATA2 Cooperates with Peroxisome Proliferator-activated Receptor-γ Depletion to Revert the Adipocyte Phenotype

Nuclear peroxisome proliferator-activated receptor-γ (PPARγ) is required for adipocyte differentiation, but its role in mature adipocytes is less clear. Here, we report that knockdown of PPARγ expression in 3T3-L1 adipocytes returned the expression of most adipocyte genes to preadipocyte levels. Con...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schupp, Michael, Cristancho, Ana G., Lefterova, Martina I., Hanniman, Elyisha A., Briggs, Erika R., Steger, David J., Qatanani, Mohammed, Curtin, Joshua C., Schug, Jonathan, Ochsner, Scott A., McKenna, Neil J., Lazar, Mitchell A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Molecular Basis of Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666598/
https://ncbi.nlm.nih.gov/pubmed/19136559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809498200
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