PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

Peroxisome proliferator-activated receptor γ(PPARγ), a nuclear receptor and the target of anti-diabetic thiazolinedione drugs, is known as the master regulator of adipocyte biology. Although it regulates hundreds of adipocyte genes, PPARγ binding to endogenous genes has rarely been demonstrated. Her...

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Autori principali: Lefterova, Martina I., Zhang, Yong, Steger, David J., Schupp, Michael, Schug, Jonathan, Cristancho, Ana, Feng, Dan, Zhuo, David, Stoeckert, Christian J., Liu, X. Shirley, Lazar, Mitchell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577797/
https://ncbi.nlm.nih.gov/pubmed/18981473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1709008
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