Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Listeria monocytogenes

Listeriolysin O (LLO), an hly-encoded cytolysin of Listeria monocytogenes, plays an essential role in the entry of L. monocytogenes into the host cell cytoplasm. L. monocytogenes-infected macrophages produce various proinflammatory cytokines, including interleukin-1α (IL-1α), that contribute to the...

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Huvudupphovsmän: Dewamitta, Sita R., Nomura, Takamasa, Kawamura, Ikuo, Hara, Hideki, Tsuchiya, Kohsuke, Kurenuma, Takeshi, Shen, Yanna, Daim, Sylvia, Yamamoto, Takeshi, Qu, Huixin, Sakai, Shunsuke, Xu, Yanting, Mitsuyama, Masao
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863535/
https://ncbi.nlm.nih.gov/pubmed/20194588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01143-09
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