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The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages

A genomic locus called “region of difference 1” (RD1) in Mycobacterium tuberculosis has been shown to contribute to the generation of host protective immunity as well as to the virulence of the bacterium. To gain insight into the molecular mechanism, we investigated the difference in the cytokine-in...

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Autors principals: Kurenuma, Takeshi, Kawamura, Ikuo, Hara, Hideki, Uchiyama, Ryosuke, Daim, Sylvia, Dewamitta, Sita Ramyamali, Sakai, Shunsuke, Tsuchiya, Kohsuke, Nomura, Takamasa, Mitsuyama, Masao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737993/
https://ncbi.nlm.nih.gov/pubmed/19596775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00015-09
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