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The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages

A genomic locus called “region of difference 1” (RD1) in Mycobacterium tuberculosis has been shown to contribute to the generation of host protective immunity as well as to the virulence of the bacterium. To gain insight into the molecular mechanism, we investigated the difference in the cytokine-in...

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Autori principali: Kurenuma, Takeshi, Kawamura, Ikuo, Hara, Hideki, Uchiyama, Ryosuke, Daim, Sylvia, Dewamitta, Sita Ramyamali, Sakai, Shunsuke, Tsuchiya, Kohsuke, Nomura, Takamasa, Mitsuyama, Masao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737993/
https://ncbi.nlm.nih.gov/pubmed/19596775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00015-09
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