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Antigen-Presenting Dendritic Cells Rescue CD4-Depleted CCR2(−/−) Mice from Lethal Histoplasma capsulatum Infection

Excessive production of interleukin-4 impairs clearance of the fungal pathogen Histoplasma capsulatum in mice lacking the chemokine receptor CCR2. An increase in the interleukin-4 level is associated with decreased recruitment of dendritic cells to lungs; therefore, we investigated the possibility t...

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Autors principals: Szymczak, Wendy A., Deepe, George S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863525/
https://ncbi.nlm.nih.gov/pubmed/20194586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00065-10
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