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Antigen-Presenting Dendritic Cells Rescue CD4-Depleted CCR2(−/−) Mice from Lethal Histoplasma capsulatum Infection
Excessive production of interleukin-4 impairs clearance of the fungal pathogen Histoplasma capsulatum in mice lacking the chemokine receptor CCR2. An increase in the interleukin-4 level is associated with decreased recruitment of dendritic cells to lungs; therefore, we investigated the possibility t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863525/ https://ncbi.nlm.nih.gov/pubmed/20194586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00065-10 |
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