CCR7 Deficiency Leads to Leukocyte Activation and Increased Clearance in Response to Pulmonary Pseudomonas aeruginosa Infection

CCR7 is a chemokine receptor expressed on the surfaces of T cells, B cells, and mature dendritic cells that controls cell migration in response to the cognate ligands CCL19 and CCL21. CCR7 is critical for the generation of an adaptive T cell response. However, the roles of CCR7 in the host defense a...

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Bibliographic Details
Main Authors: Eppert, Bryan L., Motz, Gregory T., Wortham, Brian W., Flury, Jennifer L., Borchers, Michael T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863523/
https://ncbi.nlm.nih.gov/pubmed/20176793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00962-09
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