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Anthrax Lethal Toxin Impairs CD1d-Mediated Antigen Presentation by Targeting the Extracellular Signal-Related Kinase 1/2 Mitogen-Activated Protein Kinase Pathway

Lethal toxin (LT) is a critical virulence factor of Bacillus anthracis and an important means by which this bacterium evades the host's immune system. In this study, we demonstrate that CD1d-expressing cells treated with LT have reduced CD1d-mediated antigen presentation. We earlier showed an i...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Khan, Masood A., Gallo, Richard M., Brutkiewicz, Randy R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863516/
https://ncbi.nlm.nih.gov/pubmed/20194602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01307-09
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