Highly Persistent and Effective Prime/Boost Regimens against Tuberculosis That Use a Multivalent Modified Vaccine Virus Ankara-Based Tuberculosis Vaccine with Interleukin-15 as a Molecular Adjuvant

Novel immunization strategies are needed to enhance the global control of tuberculosis (TB). In this study, we assessed the immunizing activity of a recombinant modified vaccinia Ankara (MVA) construct (MVA/IL-15/5Mtb) which overexpresses five Mycobacterium tuberculosis antigens (antigen 85A, antige...

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Detalhes bibliográficos
Main Authors: Kolibab, Kristopher, Yang, Amy, Derrick, Steven C., Waldmann, Thomas A., Perera, Liyanage P., Morris, Sheldon L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863387/
https://ncbi.nlm.nih.gov/pubmed/20357059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00006-10
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