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Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers
BACKGROUND: Alcohol and tobacco dependence are highly comorbid disorders, with preclinical evidence suggesting a role for nicotinic acetylcholine receptors (nAChRs) in alcohol consumption. Varenicline, a partial nicotinic agonist with high affinity for the α4β2 nAChR receptor, reduced ethanol intake...
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Hauptverfasser: | , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2009
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863311/ https://ncbi.nlm.nih.gov/pubmed/19249750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.01.029 |
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