Novel Components of an Active Mitochondrial K(+)/H(+) Exchange

Defects of the mitochondrial K(+)/H(+) exchanger (KHE) result in increased matrix K(+) content, swelling, and autophagic decay of the organelle. We have previously identified the yeast Mdm38 and its human homologue LETM1, the candidate gene for seizures in Wolf-Hirschhorn syndrome, as essential comp...

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Main Authors: Zotova, Ludmila, Aleschko, Markus, Sponder, Gerhard, Baumgartner, Roland, Reipert, Siegfried, Prinz, Monika, Schweyen, Rudolf J., Nowikovsky, Karin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863244/
https://ncbi.nlm.nih.gov/pubmed/20197279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059956
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