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Conformational Changes of the HIV-1 Envelope Protein during Membrane Fusion Are Inhibited by the Replacement of Its Membrane-spanning Domain

To help understand the dynamic nature of membrane fusion induced by the human immunodeficiency virus-1 (HIV-1) envelope protein, we developed a new cell-based real-time assay system employing a pair of novel reporter proteins. The reporter proteins consist of a pair of split Renilla luciferase (spRL...

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Autori principali: Kondo, Naoyuki, Miyauchi, Kosuke, Meng, Fanxia, Iwamoto, Aikichi, Matsuda, Zene
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863243/
https://ncbi.nlm.nih.gov/pubmed/20197275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067090
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