The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation

Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation and constriction of the cytokinetic ring. PC190723 is an effective bactericidal cell division in...

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Detalhes bibliográficos
Main Authors: Andreu, José M., Schaffner-Barbero, Claudia, Huecas, Sonia, Alonso, Dulce, Lopez-Rodriguez, María L., Ruiz-Avila, Laura B., Núñez-Ramírez, Rafael, Llorca, Oscar, Martín-Galiano, Antonio J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863232/
https://ncbi.nlm.nih.gov/pubmed/20212044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094722
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