A Novel Wilms Tumor 1 (WT1) Target Gene Negatively Regulates the WNT Signaling Pathway

Mammalian kidney development requires the functions of the Wilms tumor gene WT1 and the WNT/β-catenin signaling pathway. Recent studies have shown that WT1 negatively regulates WNT/β-catenin signaling, but the molecular mechanisms by which WT1 inhibits WNT/β-catenin signaling are not completely unde...

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Detalhes bibliográficos
Main Authors: Kim, Myoung Shin, Yoon, Seung Kew, Bollig, Frank, Kitagaki, Jirouta, Hur, Wonhee, Whye, Nathan J., Wu, Yun-Ping, Rivera, Miguel N., Park, Jik Young, Kim, Ho-Shik, Malik, Karim, Bell, Daphne W., Englert, Christoph, Perantoni, Alan O., Lee, Sean Bong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863207/
https://ncbi.nlm.nih.gov/pubmed/20220130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094334
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