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The Wilms’ tumor gene Wt1 is required for normal development of the retina

The Wilms’ tumor gene Wt1 is known for its important functions during genitourinary and mesothelial formation. Here we show that Wt1 is necessary for neuronal development in the vertebrate retina. Mouse embryos with targeted disruption of Wt1 exhibit remarkably thinner retinas than age-matched wild-...

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Autori principali: Wagner, Kay-Dietrich, Wagner, Nicole, Vidal, Valerie P.I., Schley, Gunnar, Wilhelm, Dagmar, Schedl, Andreas, Englert, Christoph, Scholz, Holger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125354/
https://ncbi.nlm.nih.gov/pubmed/11889045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1398
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