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Multiple Pathways for Protein Phosphatase 1 (PP1) Regulation of Na-K-2Cl Cotransporter (NKCC1) Function: THE N-TERMINAL TAIL OF THE Na-K-2Cl COTRANSPORTER SERVES AS A REGULATORY SCAFFOLD FOR Ste20-RELATED PROLINE/ALANINE-RICH KINASE (SPAK) AND PP1
The Na-K-2Cl cotransporter (NKCC1) participates in epithelial transport and in cell volume maintenance by mediating the movement of ions and water across plasma membranes. Functional studies have previously demonstrated that NKCC1 activity is stimulated by protein phosphatase 1 (PP1) inhibitors. In...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863198/ https://ncbi.nlm.nih.gov/pubmed/20223824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112672 |
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