Parathyroid Hormone Receptor Directly Interacts with Dishevelled to Regulate β-Catenin Signaling and Osteoclastogenesis

Bone growth and remodeling depend upon the opposing rates of bone formation and resorption. These functions are regulated by intrinsic seven transmembrane-spanning receptors, the parathyroid hormone receptor (PTH1R) and frizzled (FZD), through their respective ligands, parathyroid hormone (PTH) and...

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Bibliographic Details
Main Authors: Romero, Guillermo, Sneddon, W. Bruce, Yang, Yanmei, Wheeler, David, Blair, Harry C., Friedman, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863183/
https://ncbi.nlm.nih.gov/pubmed/20212039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102970
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