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Na/H Exchanger Regulatory Factors Control Parathyroid Hormone Receptor Signaling by Facilitating Differential Activation of Gα Protein Subunits

The Na/H exchanger regulatory factors, NHERF1 and NHERF2, are adapter proteins involved in targeting and assembly of protein complexes. The parathyroid hormone receptor (PTHR) interacts with both NHERF1 and NHERF2. The NHERF proteins toggle PTHR signaling from predominantly activation of adenylyl cy...

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Autors principals: Wang, Bin, Ardura, Juan A., Romero, Guillermo, Yang, Yanmei, Hall, Randy A., Friedman, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930697/
https://ncbi.nlm.nih.gov/pubmed/20562104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147785
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