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Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer

We present a liquid chromatography-mass spectrometry (LC-MS) method that capitalizes on the mass-resolving power of the orbitrap to enable sensitive and specific measurement of known and unanticipated metabolites in parallel, with a focus on water soluble species involved in core metabolism. The rev...

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Detalhes bibliográficos
Main Authors: Lu, Wenyun, Clasquin, Michelle F., Melamud, Eugene, Amador-Noguez, Daniel, Caudy, Amy A., Rabinowitz, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863137/
https://ncbi.nlm.nih.gov/pubmed/20349993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902837x
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