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Reduced Sox9 function promotes heart valve calcification phenotypes in vivo

RATIONALE: Calcification of heart valve structures is the most common form of valvular disease and is characterized by the appearance of bone-like phenotypes within affected structures. Despite the clinical significance, the underlying etiology of disease onset and progression is largely unknown and...

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Main Authors: Peacock, Jacqueline D, Levay, Agata K, Gillaspie, Devin B, Tao, Ge, Lincoln, Joy
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863131/
https://ncbi.nlm.nih.gov/pubmed/20056916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213702
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