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Matrix imbalance by inducing expression of metalloproteinase and oxidative stress in cochlea of hyperhomocysteinemic mice

Clinical study reports hearing loss in patients with low folic acid (FA) and elevated homocysteine (Hcy). We hypothesize that elevated Hcy induces imbalance in matrix turnover and oxidative stress in cochlea. Cystathione β-synthase heterozygous knockout mice were used as model for hyperhomocysteinem...

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書誌詳細
主要な著者: Kundu, Soumi, Tyagi, Neetu, Sen, Utpal, Tyagi, Suresh C.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863042/
https://ncbi.nlm.nih.gov/pubmed/19590937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0194-2
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