Genome-wide association study identifies five loci associated with lung function

Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV(1)) and the ratio of FEV(1) to forced vital capacity (FVC) in the SpiroMeta conso...

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Detalhes bibliográficos
Main Authors: Repapi, Emmanouela, Sayers, Ian, Wain, Louise V, Burton, Paul R, Johnson, Toby, Obeidat, Ma’en, Zhao, Jing Hua, Ramasamy, Adaikalavan, Zhai, Guangju, Vitart, Veronique, Huffman, Jennifer E, Igl, Wilmar, Albrecht, Eva, Deloukas, Panos, Henderson, John, Granell, Raquel, McArdle, Wendy L, Rudnicka, Alicja R, Barroso, Inês, Loos, Ruth J F, Wareham, Nicholas J, Mustelin, Linda, Rantanen, Taina, Surakka, Ida, Imboden, Medea, Wichmann, H Erich, Grkovic, Ivica, Jankovic, Stipan, Zgaga, Lina, Hartikainen, Anna-Liisa, Peltonen, Leena, Gyllensten, Ulf, Johansson, Åsa, Zaboli, Ghazal, Campbell, Harry, Wild, Sarah H, Wilson, James F, Gläser, Sven, Homuth, Georg, Völzke, Henry, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Polašek, Ozren, Rudan, Igor, Wright, Alan F, Heliövaara, Markku, Ripatti, Samuli, Pouta, Anneli, Naluai, Åsa Torinsson, Olin, Anna-Carin, Torén, Kjell, Cooper, Matthew N, James, Alan L, Palmer, Lyle J, Hingorani, Aroon D, Wannamethee, S Goya, Whincup, Peter H, Smith, George Davey, Ebrahim, Shah, McKeever, Tricia M, Pavord, Ian D, MacLeod, Andrew K, Morris, Andrew D, Porteous, David J, Cooper, Cyrus, Dennison, Elaine, Shaheen, Seif, Karrasch, Stefan, Schnabel, Eva, Schulz, Holger, Grallert, Harald, Bouatia-Naji, Nabila, Delplanque, Jérôme, Froguel, Philippe, Blakey, John D, Britton, John R, Morris, Richard W, Holloway, John W, Lawlor, Debbie A, Hui, Jennie, Nyberg, Fredrik, Jarvelin, Marjo-Riitta, Jackson, Cathy, Kähönen, Mika, Kaprio, Jaakko, Probst-Hensch, Nicole M, Koch, Beate, Hayward, Caroline, Evans, David M, Elliott, Paul, Strachan, David P, Hall, Ian P, Tobin, Martin D
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862965/
https://ncbi.nlm.nih.gov/pubmed/20010834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.501
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