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Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model
This study evaluated a biodegradable drug delivery system for local cancer radiotherapy consisting of a thermally sensitive elastin-like polypeptide (ELP) conjugated to a therapeutic radionuclide. Two ELPs (49 kD) were synthesized using genetic engineering to test the hypothesis that injectable biop...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862899/ https://ncbi.nlm.nih.gov/pubmed/20117157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.01.032 |
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