Spatial Regulation of Human Mesenchymal Stem Cell Differentiation in Engineered Osteochondral Constructs: Effects of Pre-Differentiation, Soluble Factors and Medium Perfusion

OBJECTIVE: The objective of the study was to investigate the combined effects of three sets of regulatory factors: cell pre-differentiation, soluble factors and medium perfusion on spatial control of human mesenchymal stem cell (hMSC) differentiation into cells forming the cartilaginous and bone reg...

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Autori principali: Grayson, Warren L, Bhumiratana, Sarindr, Chao, P. H. Grace, Hung, Clark T., Vunjak-Novakovic, Gordana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862865/
https://ncbi.nlm.nih.gov/pubmed/20175974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2010.01.008
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