Nalaganje...
Demonstration of the Equivalent Pharmacokinetic/Pharmacodynamic Dosing Strategy in a Multiple-Dose Study of Gefitinib
The goals of this investigation were to illustrate the use of pharmacokinetic (PK)/pharmacodynamic (PD) modeling strategies in drug development based on a multiple-dose study of gefitinib in a preclinical tumor model. Mice bearing subcutaneous LN229-wild-type EGFR or LN229-EGFRvIII mutant (a sensiti...
Shranjeno v:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862725/ https://ncbi.nlm.nih.gov/pubmed/19509243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0089 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|