A carregar...

Demonstration of the Equivalent Pharmacokinetic/Pharmacodynamic Dosing Strategy in a Multiple-Dose Study of Gefitinib

The goals of this investigation were to illustrate the use of pharmacokinetic (PK)/pharmacodynamic (PD) modeling strategies in drug development based on a multiple-dose study of gefitinib in a preclinical tumor model. Mice bearing subcutaneous LN229-wild-type EGFR or LN229-EGFRvIII mutant (a sensiti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Shining, Zhou, Qingyu, Gallo, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862725/
https://ncbi.nlm.nih.gov/pubmed/19509243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0089
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!