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Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer

BACKGROUND: Recently, germline variants of the melanocortin-1 receptor (MC1R) have been shown to be associated with an increased risk for BRAF mutant but not BRAF wild-type cutaneous melanoma. Similar to melanoma, BRAF mutations are also commonly found in papillary thyroid carcinomas. Furthermore, p...

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Detalhes bibliográficos
Main Authors: Bauer, Jürgen, Weng, Julie, Kebebew, Electron, Soares, Paula, Trovisco, Vitor, Bastian, Boris C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862686/
https://ncbi.nlm.nih.gov/pubmed/19493000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0625.2008.00827.x
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