Targeting the BAF57 SWI/SNF Subunit in Prostate Cancer: A Novel Platform to Control Androgen Receptor Activity

The androgen receptor (AR) is critical for disseminated prostate cancer proliferation and survival. AR activity is targeted either through prevention of ligand synthesis or through the use of antagonists that bind the COOH-terminal ligand-binding domain. Although initially effective, treatment fails...

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Bibliographische Detailangaben
Hauptverfasser: Link, Kevin A., Balasubramaniam, Sucharitha, Sharma, Ankur, Comstock, Clay E.S., Godoy-Tundidor, Sonia, Powers, Nathan, Cao, Khanh H., Haelens, Annemie, Claessens, Frank, Revelo, Monica P., Knudsen, Karen E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862487/
https://ncbi.nlm.nih.gov/pubmed/18559499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6392
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