Targeting the BAF57 SWI/SNF Subunit in Prostate Cancer: A Novel Platform to Control Androgen Receptor Activity

The androgen receptor (AR) is critical for disseminated prostate cancer proliferation and survival. AR activity is targeted either through prevention of ligand synthesis or through the use of antagonists that bind the COOH-terminal ligand-binding domain. Although initially effective, treatment fails...

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Main Authors: Link, Kevin A., Balasubramaniam, Sucharitha, Sharma, Ankur, Comstock, Clay E.S., Godoy-Tundidor, Sonia, Powers, Nathan, Cao, Khanh H., Haelens, Annemie, Claessens, Frank, Revelo, Monica P., Knudsen, Karen E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862487/
https://ncbi.nlm.nih.gov/pubmed/18559499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6392
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