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Conditional Deletion of BMP7 from the Limb Skeleton Does Not Affect Bone Formation or Fracture Repair

While the osteoinductive activity of recombinant bone morphogenetic protein 7 (BMP7) is well established, evaluation of the role of endogenous BMP7 in bone formation and fracture healing has been hampered by perinatal lethality in BMP7 knockout mice. Here we employ conditional deletion of BMP7 from...

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Bibliographic Details
Main Authors: Tsuji, Kunikazu, Cox, Karen, Gamer, Laura, Graf, Daniel, Economides, Aris, Rosen, Vicki
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862367/
https://ncbi.nlm.nih.gov/pubmed/19780203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.20996
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