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Morphing low affinity ligands into high avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer
Multivalency is the increase in avidity resulting from the simultaneous interaction of multiple ligands with multiple receptors. This phenomenon, seen in antibody-antigen and virus-cell membrane interactions, is useful in designing bioinspired materials for targeted delivery of drugs or imaging agen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862343/ https://ncbi.nlm.nih.gov/pubmed/20334355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn901732h |
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