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Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
T cell receptor (TCR) binding to diverse peptide-major histocompatibility complex (pMHC) ligands results in various degrees of T cell activation. Here we analyze which binding properties of the TCR-pMHC interaction are responsible for this variation in pMHC activation potency. We have analyzed activ...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862301/ https://ncbi.nlm.nih.gov/pubmed/20137987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.11.013 |
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