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The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice
AIMS: To examine the roles of the membrane attack complex of complement and its sole membrane regulator, CD59, in atherosclerosis. METHODS: C6 (C6(−/−)) deficient and CD59a (Cd59a(−/−)) knockout mice were separately crossed onto the apolipoprotein E knockout (apoE(−/−)) background. The double knocko...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Pergamon Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862291/ https://ncbi.nlm.nih.gov/pubmed/19959238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.10.035 |
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