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Insights into heterocyclization from two highly similar enzymes

[Image: see text] The cyanobactin biosynthetic pathways pat and tru, isolated from metagenomes of marine animals, lead to diverse natural products containing heterocycles derived from Cys, Ser, and Thr. Previous work has shown that PatD and TruD are extremely broad-substrate heterocyclase enzymes. T...

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Main Authors: McIntosh, John A., Donia, Mohamed S., Schmidt, Eric W.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862276/
https://ncbi.nlm.nih.gov/pubmed/20210311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9107116
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