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A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice
The pathophysiologic pathways and clinical expression of mitochondrial DNA (mtDNA) mutations are not well understood. This is mainly the result of the heteroplasmic nature of most pathogenic mtDNA mutations and of the absence of clinically relevant animal models with mtDNA mutations. mtDNA mutations...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862214/ https://ncbi.nlm.nih.gov/pubmed/11175788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/84831 |
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