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A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice
The pathophysiologic pathways and clinical expression of mitochondrial DNA (mtDNA) mutations are not well understood. This is mainly the result of the heteroplasmic nature of most pathogenic mtDNA mutations and of the absence of clinically relevant animal models with mtDNA mutations. mtDNA mutations...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862214/ https://ncbi.nlm.nih.gov/pubmed/11175788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/84831 |
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