Urea Facilitates the Translocation of Single-Stranded DNA and RNA Through the α-Hemolysin Nanopore

The staphylococcal α-hemolysin (αHL) protein nanopore is under investigation as a fast, cheap detector for nucleic acid analysis and sequencing. Although discrimination of all four bases of DNA by the αHL pore has been demonstrated, analysis of single-stranded DNAs and RNAs containing secondary stru...

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Bibliografske podrobnosti
Main Authors: Japrung, Deanpen, Henricus, Marsiyana, Li, Qiuhong, Maglia, Giovanni, Bayley, Hagan
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Membrane
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862201/
https://ncbi.nlm.nih.gov/pubmed/20441749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4333
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