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MMP2 Genetic Variation Is Associated With Measures of Fibrous Cap Thickness: The Atherosclerosis Risk in Communities Carotid MRI Study

OBJECTIVE: Genetic variation in matrix metalloproteinase (MMP) promoter regions alters the transcriptional activity of MMPs and has been consistently associated with CHD, presumably through plaque degradation and remodeling. We examined the association of MMP promoter variation with multiple plaque...

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Detalhes bibliográficos
Main Authors: Volcik, Kelly A., Campbell, Stephen, Chambless, Lloyd E., Coresh, Josef, Folsom, Aaron R., Mosley, Thomas H., Ni, Hanyu, Wagenknecht, Lynne E., Wasserman, Bruce A., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862087/
https://ncbi.nlm.nih.gov/pubmed/20064641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2009.12.006
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