MMP2 Genetic Variation Is Associated With Measures of Fibrous Cap Thickness: The Atherosclerosis Risk in Communities Carotid MRI Study

OBJECTIVE: Genetic variation in matrix metalloproteinase (MMP) promoter regions alters the transcriptional activity of MMPs and has been consistently associated with CHD, presumably through plaque degradation and remodeling. We examined the association of MMP promoter variation with multiple plaque...

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Huvudupphovsmän: Volcik, Kelly A., Campbell, Stephen, Chambless, Lloyd E., Coresh, Josef, Folsom, Aaron R., Mosley, Thomas H., Ni, Hanyu, Wagenknecht, Lynne E., Wasserman, Bruce A., Boerwinkle, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862087/
https://ncbi.nlm.nih.gov/pubmed/20064641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2009.12.006
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