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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

In vivo studies suggest that replication forks are arrested due to encounters with head-on transcription complexes. Yet, the fate of the replisome and RNA polymerase (RNAP) following a head-on collision is unknown. Here, we find that the E. coli replisome stalls upon collision with a head-on transcr...

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Autors principals: Pomerantz, Richard T., O’Donnell, Mike
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861996/
https://ncbi.nlm.nih.gov/pubmed/20110508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1179595
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