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Mechanism of Action of 2-Mercapto-1(β-4-pyridethyl)benzimidazole: A Reversible Inhibitor of Interferon Activity

2-mercapto-1(β-4-pyridethyl)benzimidazole (MPB) inhibited the development of antiviral activity induced by interferon in chick cells. The MPB effect was reversed by washing the cells. The action of MPB was on a step immediately following interferon binding but before the cellular RNA and protein syn...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Friedman, Robert M., Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4313191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.1.104
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