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Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials

IMPORTANCE OF THE FIELD: Ceramide accumulation has been shown to be a conserved mechanism of apoptosis initiation in normal physiological processes as well as in response to cancer treatments such as radiation and chemotherapy. Therefore, it is unsurprising that many cancers develop aberrations of s...

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Autors principals: Beckham, Thomas H, Elojeimy, Saeed, Cheng, Joseph C, Turner, Lorianne S., Hoffman, Stanley, Norris, James S, Liu, Xiang
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861896/
https://ncbi.nlm.nih.gov/pubmed/20334489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728221003752768
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