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Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials
IMPORTANCE OF THE FIELD: Ceramide accumulation has been shown to be a conserved mechanism of apoptosis initiation in normal physiological processes as well as in response to cancer treatments such as radiation and chemotherapy. Therefore, it is unsurprising that many cancers develop aberrations of s...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861896/ https://ncbi.nlm.nih.gov/pubmed/20334489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728221003752768 |
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