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Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials

IMPORTANCE OF THE FIELD: Ceramide accumulation has been shown to be a conserved mechanism of apoptosis initiation in normal physiological processes as well as in response to cancer treatments such as radiation and chemotherapy. Therefore, it is unsurprising that many cancers develop aberrations of s...

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Detalhes bibliográficos
Main Authors: Beckham, Thomas H, Elojeimy, Saeed, Cheng, Joseph C, Turner, Lorianne S., Hoffman, Stanley, Norris, James S, Liu, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861896/
https://ncbi.nlm.nih.gov/pubmed/20334489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728221003752768
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