IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses

CD4(pos) T helper (Th) 2 cells secrete interleukin (IL)-4, IL-5 and IL-13 and are required for immunity to gastrointestinal helminth infections1. However, Th2 cells also promote chronic inflammation associated with asthma and allergic disorders2. The non-hematopoietic cell-derived cytokines thymic s...

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Detalhes bibliográficos
Main Authors: Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861732/
https://ncbi.nlm.nih.gov/pubmed/20200520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08901
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