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Cellular Localization of the Herpes Simplex Virus ICP0 Protein Dictates Its Ability to Block IRF3-Mediated Innate Immune Responses

Interferon regulatory factor 3 (IRF3) is important for innate antiviral responses; accordingly, many viruses target and inactivate IRF3. The ability of the Herpes simplex virus type 1 (HSV-1) immediate early protein ICP0 to inhibit IRF3 is controversial and has not been studied solely in the context...

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Hlavní autoři: Paladino, Patrick, Collins, Susan E., Mossman, Karen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861674/
https://ncbi.nlm.nih.gov/pubmed/20454685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010428
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