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X-ray structure of AMPA-subtype glutamate receptor: symmetry and mechanism

Ionotropic glutamate receptors (iGluRs) mediate the majority of excitatory neurotransmission in the central nervous system and function by opening a transmembrane ion channel upon binding of glutamate. Despite their crucial role in neurobiology, the architecture and atomic structure of an intact iGl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sobolevsky, Alexander I., Rosconi, Michael P., Gouaux, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861655/
https://ncbi.nlm.nih.gov/pubmed/19946266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08624
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