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Analysis of Human Small Nucleolar RNAs (snoRNA) and the Development of snoRNA Modulator of Gene Expression Vectors

Human small nucleolar RNAs (snoRNAs) that copurify with nucleoli isolated from HeLa cells have been characterized. Novel fibrillarin-associated snoRNAs were detected that allowed the creation of a new vector system for the targeted knockdown of one or more genes in mammalian cells. The snoMEN (snoRN...

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Autori principali: Ono, Motoharu, Yamada, Kayo, Avolio, Fabio, Scott, Michelle S., van Koningsbruggen, Silvana, Barton, Geoffrey J., Lamond, Angus I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861615/
https://ncbi.nlm.nih.gov/pubmed/20219969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0078
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