PKMζ Inhibition Reverses Learning-Induced Increases in Hippocampal Synaptic Strength and Memory during Trace Eyeblink Conditioning

A leading candidate in the process of memory formation is hippocampal long-term potentiation (LTP), a persistent enhancement in synaptic strength evoked by the repetitive activation of excitatory synapses, either by experimental high-frequency stimulation (HFS) or, as recently shown, during actual l...

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Main Authors: Madroñal, Noelia, Gruart, Agnès, Sacktor, Todd C., Delgado-García, José M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861600/
https://ncbi.nlm.nih.gov/pubmed/20454458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010400
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