Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission

The eIF4E-binding proteins (4E-BPs) repress translation initiation by preventing eIF4F complex formation. Of the three mammalian 4E-BPs, only 4E-BP2 is enriched in the mammalian brain and plays an important role in synaptic plasticity and learning and memory formation. Here we describe asparagine de...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bidinosti, Michael, Ran, Israeli, Sanchez-Carbente, Maria R., Martineau, Yvan, Gingras, Anne-Claude, Gkogkas, Christos, Raught, Brian, Bramham, Clive, Sossin, Wayne S., Costa-Mattioli, Mauro, DesGroseillers, Luc, Lacaille, Jean-Claude, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861547/
https://ncbi.nlm.nih.gov/pubmed/20347422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados